Mariah Carey is one of the most famous singers of her time. She is 54 years old now and recently got a lot of attention for an outfit she wore. Let’s see why people are talking about her clothing choice…
Mariah Carey caught many eyes at a big event full of well-dressed celebrities. People noticed her because she wore a very bold outfit.
At the third annual Recording Academy Honors, Mariah wore a dress that some people thought was unusual. It was a cream-colored dress that fit her body closely. The dress had a corset with sheer caramel-colored tulle details. It looked very good on her.
The dress also had a deep neckline that showed off her figure in a way some people thought was not appropriate.
While many fans loved Mariah Carey’s look, with one saying, “I like it,” and another saying the dress seemed to be “MADE for her,” not everyone felt the same way.
Some people thought the dress was not appropriate for someone her age. One person commented, “Maybe in the early ’90s, Mariah, but that’s not really something you should be wearing at 54.” Another person added, “At a certain age you just need to cover it up,” and a third said, “Someone needs to remind her that she’s 54, not 24.”
Mariah Carey is used to getting critical comments online. People often leave judgmental messages on her social media. In 2017, she posted pictures of herself with her then-boyfriend Bryan Tanaka on Instagram and got many mean comments about her weight.
One person wrote, “Mariah, you need to lose some weight because you’re starting to look like a whale.” Others said she looked “like a tease” and told her to “cover those airbags” or that she “looked gross.” Mariah has received many unfair comments like these over the years.
People always have a lot of opinions about what celebrities wear. However, what really matters is how the celebrity feels in their clothes. Mariah Carey has every right to wear a dress that some people might not like.
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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