They may have been born more than a decade apart, but these siblings still have one remarkable thing in common.
Albinism is a rare genetic disorder that causes a lack of pigmentation in the skin, eyes and/or hair, giving albino people a unique look:
It’s very rare to have an albino child… which makes it remarkable that one Kazakh couple had not one, but two albino children 12 years apart.
Meet Asel and Kamila, the incredibly unique siblings that have turned into in-demand models:
Asel is the older sibling at 14. Her mother, Aiman Sarkitova, said she was stunned when she was born albino.
“When I gave birth to my eldest, genetics were not so developed with us,” she told the Daily Mail. “It is developing only now. The doctors were shocked.”
Imagine their surprise when, 12 years later, Kamila was born with the same condition.
It’s an incredible, striking sight to see these two siblings together—so the two teamed up and became a modeling duo.
Asel has already been modeling since she was 10, but with her 2-year-old sister at her side she’s become even more in-demand. The pair have over 33,000 followers on Instagram.
While their albinism has led to big success, it’s not always easy. The condition is also associated with medical conditions like a sensitivity to sunlight.
“If I go outside in the afternoon, then I definitely apply sunscreen, put on clothes to protect my skin, headgear or use an umbrella,” Asel said.
“In the evening, when there is almost no sun, it’s much easier for me.”
But through whatever ups and downs life throws at them, they’ll always have each other.
The condition is so rare that albino people can feel alone, but these two sisters are lucky that they’ll always have a family member just like them.
And hopefully, their success as models will shed some light on albinism and show how uniquely beautiful albino people can be.
“Many people do not know what albinos are,” Asel said.
We think these sisters are stunning! Share this remarkable story and beautiful photos!
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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